Sodium bicarbonate supplementation and its impact on endurance performance: A PRISMA-guided systematic review

Authors

DOI:

https://doi.org/10.65575/jamss.v1i3.8

Keywords:

Sodium Bicarbonate, Endurance, Performance, Muscle Fatigue

Abstract

Background

Sodium bicarbonate (NaHCO₃) has gained substantial attention as an ergogenic aid due to its buffering capacity, which helps mitigate exercise-induced metabolic acidosis. Its use has been widely explored in high-intensity sports where the accumulation of hydrogen ions contributes to early muscle fatigue and decreased performance.

Objectives

This systematic review aims to synthesize current empirical evidence regarding the effectiveness of sodium bicarbonate supplementation in enhancing endurance-related performance outcomes, with a particular focus on its role in delaying muscle fatigue during exercise.

Methods

A Systematic Literature Review (SLR) was conducted following the PRISMA guidelines. Article identification and selection employed the PICO framework. Relevant studies were retrieved from Scopus, ScienceDirect, Web of Science, and PubMed using the keywords “sodium bicarbonate,” “endurance,” “performance,” and “muscle fatigue.” Nine peer-reviewed studies met the inclusion criteria and were analyzed descriptively to evaluate the effects of sodium bicarbonate on athletic performance.

Results

The findings indicate that sodium bicarbonate supplementation can enhance performance, particularly in high-intensity and short-to-medium-duration activities. However, its effectiveness is highly context-dependent and influenced by exercise modality, duration and intensity, athlete training status, and supplementation protocol—including dosage, timing, and individual physiological tolerance. Several studies employed relatively small and homogeneous samples, limiting the generalizability of the results.

Conclusion

Sodium bicarbonate shows consistent potential as an ergogenic supplement for improving endurance-related performance by attenuating metabolic fatigue. Nonetheless, its benefits are not uniform across all athletes or sport types. Optimal outcomes appear to require individualized dosing strategies and sport-specific application. This review provides an updated synthesis of evidence on sodium bicarbonate supplementation and highlights critical variables that moderate its effectiveness. The study underscores the need for individualized supplementation protocols and encourages future research employing larger, more diverse athlete populations and standardized ergogenic assessment methods.

References

Abdulkader, H. K., Sultana, D., Valappil, I. N. K., Vishnulal, B. M., Anto, A. C., & Amalesh, P. J. (2024). Effect of pre-exercise self myofascial release on symptoms of delayed muscle soreness and flexibility. Journal of Physical Education and Sport, 24(10), 1426–1433. https://doi.org/10.7752/jpes.2024.10268

Aktitiz, S., Koşar, Ş. N., & Turnagöl, H. H. (2024). Effects of acute and multi-day low-dose sodium bicarbonate intake on high-intensity endurance exercise performance in male recreational cyclists. European Journal of Applied Physiology, 124(7), 2111–2122. https://doi.org/10.1007/s00421-024-05434-1

Apollaro, G., Franchini, E., Falcó, C., Detanico, D., & Kons, R. L. (2023). Sport-Specific Tests for Endurance in Taekwondo: A Narrative Review With Guidelines for the Assessment. Strength & Conditioning Journal. https://doi.org/10.1519/SSC.0000000000000828

Bachero-Mena, B., & González-Badillo, J. J. (2021). Mechanical and Metabolic Responses during High-intensity Training in Elite 800-m Runners. International Journal of Sports Medicine, 42(04), 350–356. https://doi.org/10.1055/a-1273-8564

Badaruddin, R., Salikunna, N. A., Ramadhan, M. Z., Tanra, A. A. M., & Muslimin, I. (2023). The Impact of Carbonated Sodium Bicarbonate Drinks on Physical Fitness in Adolescents. Scientific Journal of Medical Faculty of Halu Oleo University, 11(1), 20–26.

Cairns, S. P., & Renaud, J. (2023). The potassium–glycogen interaction on force and excitability in mouse skeletal muscle: implications for fatigue. The Journal of Physiology, 601(24), 5669–5687. https://doi.org/10.1113/JP285129

Dalton, B., Hester, G., Alesi, M., McDougle, J., Cooper, M., VanDusseldorp, T., Buresh, R., & Feito, Y. (2024). Central and peripheral neuromuscular fatigue following ramp and rapid maximal voluntary isometric contractions. Frontiers in Physiology, 15. https://doi.org/10.3389/fphys.2024.1434473

Delextrat, A., Mackessy, S., Arceo-Rendon, L., Scanlan, A., Ramsbottom, R., & Calleja-Gonzalez, J. (2018). Effects of Three-Day Serial Sodium Bicarbonate Loading on Performance and Physiological Parameters During a Simulated Basketball Test in Female University Players. International Journal of Sport Nutrition and Exercise Metabolism, 28(5), 547–552. https://doi.org/10.1123/ijsnem.2017-0353

Durkalec-Michalski, K., Nowaczyk, P. M., Adrian, J., Kamińska, J., & Podgórski, T. (2020). The influence of progressive-chronic and acute sodium bicarbonate supplementation on anaerobic power and specific performance in team sports: a randomized, double-blind, placebo-controlled crossover study. Nutrition & Metabolism, 17(1), 38. https://doi.org/10.1186/s12986-020-00457-9

Fadilah, R. N., & Widodo, A. (2023). Analisis Kondisi Fisik Atlet Cabang Olahraga Taekwondo Pada Persiapan Pon Xx Papua 2021. Jurnal Multilingual, 3(3), 515–529. https://ejournal.penerbitjurnal.com/index.php/multilingual/article/view/464%0Ahttps://ejournal.penerbitjurnal.com/index.php/multilingual/article/download/464/404

Gholami, M. (2023). The Effect of Massage on the Exhausted Aerobic Exercise-Induced Muscle Damage Indicators in Healthy Young Men. Journal of Health Reports and Technology, 9(4). https://doi.org/10.5812/jhrt-137253

Grgic, J., Pedisic, Z., Saunders, B., Artioli, G. G., Schoenfeld, B. J., McKenna, M. J., Bishop, D. J., Kreider, R. B., Stout, J. R., Kalman, D. S., Arent, S. M., VanDusseldorp, T. A., Lopez, H. L., Ziegenfuss, T. N., Burke, L. M., Antonio, J., & Campbell, B. I. (2021). International Society of Sports Nutrition position stand: sodium bicarbonate and exercise performance. Journal of the International Society of Sports Nutrition, 18(1). https://doi.org/10.1186/s12970-021-00458-w

Gurton, W. H., Gough, L. A., Siegler, J. C., Lynn, A., & Ranchordas, M. K. (2024). Oral but Not Topical Sodium Bicarbonate Improves Repeated Sprint Performance During Simulated Soccer Match Play Exercise in Collegiate Athletes. International Journal of Sport Nutrition and Exercise Metabolism, 34(6), 362–371. https://doi.org/10.1123/ijsnem.2024-0059

Hadjarati, H., & Massa, R. S. (2023). The effect of isotonic drink on heart rates recovery after pencak silat activity: a study on female students in an islamic boarding school. Jurnal Keolahragaan, 11(1), 58–65. https://doi.org/10.21831/jk.v11i1.54248

Hanada, T. Z. B., Knack, R., Mayr, K., Knack, R. S., Guedes, D., Scorcine, C., & Pereira, R. (2023). Analysis of the use of Sodium Bicarbonate for the performance of surfing athletes. https://doi.org/10.32388/5WBMHS

Insam, H., & Chidley, J. (2024). The effects of sodium bicarbonate ingestion and sports performance in female athletes during different phases of the menstrual cycle. Graduate Journal of Sports Science, Coaching, Management, & Rehabilitation, 1(3), 28–28. https://doi.org/10.19164/gjsscmr.v1i3.1520

Jurić, I., Labor, S., Plavec, D., & Labor, M. (2019). Inspiratory muscle strength affects anaerobic endurance in professional athletes. Archives of Industrial Hygiene and Toxicology, 70(1), 42–48. https://doi.org/10.2478/aiht-2019-70-3182

Katmawanti, S., Hanim, S., Sharoni, S. K. A., Fauzi, R., Samah, D. A., & Wahyuni, O. S. (2022). What alternative supplements are prominent between some of female athletes?: A systematic review. Journal of Physical Education and Sport, 22(12), 3101–3113. https://doi.org/10.7752/jpes.2022.12393

Kim, J.-W., & Nam, S.-S. (2021). Physical Characteristics and Physical Fitness Profiles of Korean Taekwondo Athletes: A Systematic Review. International Journal of Environmental Research and Public Health, 18(18), 9624. https://doi.org/10.3390/ijerph18189624

Kreutzer, A., Graybeal, A. J., Moss, K., Braun-Trocchio, R., & Shah, M. (2022). Caffeine Supplementation Strategies Among Endurance Athletes. Frontiers in Sports and Active Living, 4. https://doi.org/10.3389/fspor.2022.821750

Kristiono, A. A., Pratama, O. P. A., Islam, S., Abadi, A. K., & Wijaya, M. B. (2024). Effect of Small Side Games 3x3 on Oxygen Saturation (SpO2) in Extra-Curricular Participants Basketball SMK 1 Semarang. Proceedings of International Conference on Physical Education, Health, and Sports, 4, 109–116.

Lassen, T. A. H., Lindstrøm, L., Lønbro, S., & Madsen, K. (2021). Increased Performance in Elite Runners Following Individualized Timing of Sodium Bicarbonate Supplementation. International Journal of Sport Nutrition and Exercise Metabolism, 31(6), 453–459. https://doi.org/10.1123/ijsnem.2020-0352

LEACH, N. K., HILTON, N. P., TINNION, D., DOBSON, B., MCNAUGHTON, L. R., & SPARKS, S. A. (2023). Sodium Bicarbonate Ingestion in a Fasted State Improves 16.1-km Cycling Time-Trial Performance. Medicine & Science in Sports & Exercise, 55(12), 2299–2307. https://doi.org/10.1249/MSS.0000000000003263

Lopes-Silva, J. P., & Franchini, E. (2021). Effects of Isolated and Combined Ingestion of Sodium Bicarbonate and β-Alanine on Combat Sports Athletes’ Performance: A Systematic Review. Strength & Conditioning Journal, 43(3), 101–111. https://doi.org/10.1519/SSC.0000000000000603

Malone, S., Shovlin, A., Collins, K., McRobert, A., & Doran, D. (2021). Is the metabolic power paradigm ecologically valid within elite Gaelic football? Sport Sciences for Health, 17(3), 551–561. https://doi.org/10.1007/s11332-020-00707-6

Miguel-Ortega, Á., Calleja-González, J., & Mielgo-Ayuso, J. (2024). Endurance in Long-Distance Swimming and the Use of Nutritional Aids. Nutrients, 16(22), 3949. https://doi.org/10.3390/nu16223949

Newbury, J. W., Cole, M., Kelly, A. L., & Gough, L. A. (2024). Neither an Individualised Nor a Standardised Sodium Bicarbonate Strategy Improved Performance in High-Intensity Repeated Swimming, or a Subsequent 200 m Swimming Time Trial in Highly Trained Female Swimmers. Nutrients, 16(18), 3123. https://doi.org/10.3390/nu16183123

Nubatonis, J. D., Sulistiyono, S., Husein, M., Septianto, I., Runesi, S., Zakiah, D. M. N., Dewantara, J., Azrina, J., Islam, S., & Salacup, V. L. D. (2024). Optimizing Arm Muscle Endurance in Pencak Silat Athletes: Insights from a Literature Review. Tanjungpura Journal of Coaching Research, 2(3), 131–141. https://doi.org/10.26418/tajor.v2i3.80838

Pethick, J., & Tallent, J. (2022). The Neuromuscular Fatigue-Induced Loss of Muscle Force Control. Sports, 10(11), 184. https://doi.org/10.3390/sports10110184

Raeder, C., Kämper, M., Praetorius, A., Tennler, J.-S., & Schoepp, C. (2024). Metabolic, cognitive and neuromuscular responses to different multidirectional agility-like sprint protocols in elite female soccer players – a randomised crossover study. BMC Sports Science, Medicine and Rehabilitation, 16(1), 64. https://doi.org/10.1186/s13102-024-00856-y

Ragone, L., Guilherme Vieira, J., Camaroti Laterza, M., Leitão, L., da Silva Novaes, J., Macedo Vianna, J., & Ricardo Dias, M. (2020). Acute Effect of Sodium Bicarbonate Supplementation on Symptoms of Gastrointestinal Discomfort, Acid‐Base Balance, and Performance of Jiu‐Jitsu Athletes. Journal of Human Kinetics, 75(1), 85–93. https://doi.org/10.2478/hukin-2020-0039

Rini, R. G. M., & Purnomo, E. (2021). The differences response of massage types with variation massage pressure on running speed in POPDA Sleman athletics. Jurnal Keolahragaan, 9(2), 193–201. https://doi.org/10.21831/jk.v9i2.35808

Silva de Souza, R. A., Barreto, G., Alves Freire, P. A., de Abreu, W. C., Saunders, B., & da Silva, S. F. (2024). Sodium bicarbonate improved CrossFit® Benchmark Fran, but not subsequent 500 m rowing performance. Research in Sports Medicine, 32(6), 965–980. https://doi.org/10.1080/15438627.2024.2324254

Stepanyan, L., & Lalayan, G. (2023). Heart rate variability features and their impact on athletes’ sports performance. Journal Of Physical Education And Sport, 23(8), 2156–2163.

Sundberg, C. W., Hunter, S. K., Trappe, S. W., Smith, C. S., & Fitts, R. H. (2018). Effects of elevated H + and P i on the contractile mechanics of skeletal muscle fibres from young and old men: implications for muscle fatigue in humans. The Journal of Physiology, 596(17), 3993–4015. https://doi.org/10.1113/JP276018

Vanderheyden, L. W., McKie, G. L., Howe, G. J., & Hazell, T. J. (2020). Greater lactate accumulation following an acute bout of high-intensity exercise in males suppresses acylated ghrelin and appetite postexercise. Journal of Applied Physiology, 128(5), 1321–1328. https://doi.org/10.1152/japplphysiol.00081.2020

Varovic, D., Grgic, J., Schoenfeld, B. J., & Vuk, S. (2023). Ergogenic Effects of Sodium Bicarbonate on Resistance Exercise: A Randomized, Double-Blind, Placebo-Controlled Study. Journal of Strength and Conditioning Research. https://doi.org/10.1519/JSC.0000000000004443

Wang, J., Qiu, J., Yi, L., Hou, Z., Benardot, D., & Cao, W. (2019). Effect of sodium bicarbonate ingestion during 6 weeks of HIIT on anaerobic performance of college students. Journal of the International Society of Sports Nutrition, 16(1). https://doi.org/10.1186/s12970-019-0285-8

Yolanda, Y., Haetami, M., Yanti, N., Abdulsatar, A. A., & Abdullah, M. M. (2025). Analysis of Athlete Endurance: A Study on Female Volleyball Athletes. Khatulistiwa Journal of Sport Science, 1(1), 18–24.

Zagatto, A. M., Bishop, D. J., Antunes, B. M., Beck, W. R., Malta, E. S., de Poli, R. A. B., Cavaglieri, C. R., Chacon‐Mikahil, M. P. T., & Castro, A. (2022). Impacts of high‐intensity exercise on the metabolomics profile of human skeletal muscle tissue. Scandinavian Journal of Medicine & Science in Sports, 32(2), 402–413. https://doi.org/10.1111/sms.14086

Zamri, F. N. S., Linoby, A., Norhamazi, I., Mursyid, S., Naimah, M., Haslan, A. N., & Noor, M. A. M. (2022). Fruit-derived Polyphenol supplementation improves exercise performance: a meta-analysis of 29 randomised controlled trials. Journal of Physical Education and Sport, 22(9), 2120–2126. https://doi.org/10.7752/jpes.2022.09271

Published

2025-11-30

How to Cite

Islam, S., Husein, M., Demetrimus Nubatoni, J. ., Azizah Awaliyyah, U. ., Gemilang Muti, G., & Atmaja, A. R. D. . (2025). Sodium bicarbonate supplementation and its impact on endurance performance: A PRISMA-guided systematic review. Journal of Applied Movement and Sport Science, 1(3), 39-47. https://doi.org/10.65575/jamss.v1i3.8